Low coherence interferometry approach for aiding fine needle aspiration biopsies.

نویسندگان

  • Ernest W Chang
  • Joseph Gardecki
  • Martha Pitman
  • Eric J Wilsterman
  • Ankit Patel
  • Guillermo J Tearney
  • Nicusor Iftimia
چکیده

We present portable preclinical low-coherence interference (LCI) instrumentation for aiding fine needle aspiration biopsies featuring the second-generation LCI-based biopsy probe and an improved scoring algorithm for tissue differentiation. Our instrument and algorithm were tested on 38 mice with cultured tumor mass and we show the specificity, sensitivity, and positive predictive value of tumor detection of over 0.89, 0.88, and 0.96, respectively.

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عنوان ژورنال:
  • Journal of biomedical optics

دوره 19 11  شماره 

صفحات  -

تاریخ انتشار 2014